Trypanosomiasis

Trypanosomiasis

Trypanosomiasis is the group of disease caused by protozoa genus trypanosoma affect all domestic animals.

Trypanosomiasis causing parasites
Trypanosomiasis causing parasites

Developmental stage

Trypomastigote stage

  • A blade like form with kinetoplast posterior to the nucleus and usually near the posterior extremity. An undulating membrane is well developed and free flagellum is often present.
  • This stage usually found in vertebrate host and also in arthropods.

Epimastigote stage

  • Kinetoplast and axoneme lie anterior to the nucleus and undulating membrane is short.
  • In few species, this stage found in vertebrate host, but principally in arthropods.

Promastigote stage

  • Kinetoplast and axoneme are at the anterior tip of body with no undulating membrane.
  • It is found in arthropods.

Amastigote stage

  • Rounded body with kinetoplast.
  • Absence of flagellum (or with short fibrils).
  • Found in arthropods.

Transmission

Cyclical transmission

  1. Anterior station development/ Salivarian transmission- highly pathogenic,  the trypanosome multiply in digestive tract and proboscis, so new infection is transmitted when feeding. e.g  T.congolense, T.vivax and T.brucei
  2. Posterior station development/stercorarian transmission- non pathogenic  the multiplication and transformation of trypanosomes  occur in gut and the infective forms migrate to the rectum and passed with the faeces. e.g. T.melophagium , T.theileri and T.cruzi

Non cyclical/Mechanical transmission

  • The trypanosomes are transmitted from one mammalin host to another by interrupted feeding of biting insects e.g. Tabanus sp and stomoxys sp.
  • The trypanosomes transmitted by bite of vampire bat also can occur e.g. T.evansi.
  • Mechanical transmission can also occur in some salivarian group, transmitted cyclically in tse-tse flies. Eg. T. vivax and T. brucei.
  • Dog, cat and wild carnivores infected by ingestion of tissue from infected fresh carcass, died of trypanosomiasis.
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