Trypanosomiasis
Trypanosomiasis is the group of disease caused by protozoa genus trypanosoma affect all domestic animals.
Developmental stage
Trypomastigote stage
- A blade like form with kinetoplast posterior to the nucleus and usually near the posterior extremity. An undulating membrane is well developed and free flagellum is often present.
- This stage usually found in vertebrate host and also in arthropods.
Epimastigote stage
- Kinetoplast and axoneme lie anterior to the nucleus and undulating membrane is short.
- In few species, this stage found in vertebrate host, but principally in arthropods.
Promastigote stage
- Kinetoplast and axoneme are at the anterior tip of body with no undulating membrane.
- It is found in arthropods.
Amastigote stage
- Rounded body with kinetoplast.
- Absence of flagellum (or with short fibrils).
- Found in arthropods.
Transmission
Cyclical transmission
- Anterior station development/ Salivarian transmission- highly pathogenic, the trypanosome multiply in digestive tract and proboscis, so new infection is transmitted when feeding. e.g T.congolense, T.vivax and T.brucei
- Posterior station development/stercorarian transmission- non pathogenic the multiplication and transformation of trypanosomes occur in gut and the infective forms migrate to the rectum and passed with the faeces. e.g. T.melophagium , T.theileri and T.cruzi
Non cyclical/Mechanical transmission
- The trypanosomes are transmitted from one mammalin host to another by interrupted feeding of biting insects e.g. Tabanus sp and stomoxys sp.
- The trypanosomes transmitted by bite of vampire bat also can occur e.g. T.evansi.
- Mechanical transmission can also occur in some salivarian group, transmitted cyclically in tse-tse flies. Eg. T. vivax and T. brucei.
- Dog, cat and wild carnivores infected by ingestion of tissue from infected fresh carcass, died of trypanosomiasis.