Pancreatic Polypeptide

Pancreatic Polypeptide

Pancreatic Polypeptide increases gut motility and gastric emptying, stimu­lates the secretions of the intestinal hormones like gastrin, secretin and CCK.

Pancreatic polypeptide is a peptide hormone, containing 36 amino acids and secreted by the stimulation of F (PP) cells in the islets of Pancreas.

It is related to two other 36 amino acid polypeptides – polypeptide YY (PYY) of intestine and neuropeptide Y (NPY)of brain and ANS.

It inhibits pancreatic enzyme secretion and gall bladder contraction. Somatostatin inhibits its release.

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