Lymphocytes of Animals
Lymphocytes cells are characterized by well defined centrally placed nucleus, surrounded by cytoplasm. According to the size and the ratio of nucleus to cytoplasm, these cells are further divided into 3 types-
- Small lymphocytes: These are small sized cells with a large notched nucleus.
- Medium lymphocytes: These are medium sized, which have notched nucleus surrounded by thin rim of cytoplasm.
- Large lymphocytes: These have comparatively small sized nucleus with broad rim of cytoplasm.
Lymphocytes are actively motile cells with amoeboid movement and are mainly concerned with the development of immunity against specific disease organisms. They have no phagocytic properties.
Abnormalities in Lymphocytes
Lymphocytosis
Lymphocytosis condition indicates increased number of lymphocytes in the circulation, which is common in viral infection (eg) infectious hepatitis.
Lymphopenia
Lymphopenia condition indicates decreased number of lymphocytes in circulation and is seen in cases of TB, acute stress and glucocorticoid injection.